Dementia could start in your blood vessels - eat these foods to keep your mind sharp | Dr William Li

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Published 2024-05-23
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55 million people suffer dementia worldwide with numbers expected to double every 20 years. Understanding the link between our heart health and brain function is critical, illuminating the profound impact that heart health has on preventing dementia.

Dr. William Li, an expert in cardiovascular and metabolic health. He reveals how caring for our heart is not just about longevity but maintaining sharp, effective brain function as we age. His groundbreaking work has impacted more than seventy diseases including diabetes, heart disease, and obesity. Dr. Li is also a New York Times best-selling author.

In today’s episode, Dr. Li explains how simple lifestyle choices in diet, exercise and sleep can drastically shape our brain's health and stave off dementia.

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Timecodes:
00:00 Introduction
01:15 Quickfire questions
03:59 Understanding dementia and Alzheimer's disease
05:24 Symptoms distinguishing dementia from ageing
07:10 The role of blood vessels in brain health
08:31 How circulation affects brain function
10:07 What causes blood clots and strokes?
11:18 What is the blood-brain barrier?
11:59 The importance of maintaining healthy blood vessels
13:18 The impact of lifestyle choices on brain health
16:20 What happens in our brains when we sleep?
20:51 What is the glymphatic system?
23:54 Vascular dementia may be the most common form of dementia
25:51 The role of glucose in brain function
28:25 What causes dementia and why does it happen when we get older?
30:13 Preventing dementia with lifestyle changes
32:33 What are healthy blood vessels like?
40:36 The surprising role of EPCs in brain repair
44:17 Can you slow down or reverse dementia?
50:09 Using food as medicine
52:08 The connection between gut health and brain health
54:30 The importance of exercise for brain health
59:26 How to avoid dementia
01:04:12 The link between mental health and cardiovascular disease

📚 Dr. William Li’s books:
- Eat to Beat Disease: amzn.to/3Vf8ar9
- Eat to Beat Your Diet: amzn.to/3VhEPwq

đź“š Books from our ZOE Scientists:
- Every Body Should Know This by Dr Federica Amati: amzn.to/4blJsLg
- Recipes for a Better Menopause by Dr Federica Amati: amzn.to/4aAzox0
- Food For Life by Prof. Tim Spector: amzn.to/455DqMz

Relevant studies:
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk, published in Nature
Link: www.nature.com/articles/s41586-021-04369-3

Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images, published in Science
Link: www.science.org/doi/10.1126/science.abn6598

Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study—a randomized controlled trial, published in The American Journal of Clinical Nutrition
Link: www.sciencedirect.com/science/article/pii/S0002916…

Have feedback or a topic you'd like us to cover? Let us know here:
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Episode transcripts are available here: zoe.com/learn/category/podcasts

All Comments (21)
  • I never drink alcohol and never smoked in my entire life! Never took drugs.... and always nourished myself with a Mediterranean diet! .... My parents were born in Italy and they always cultivated a vegetable garden as long as I can remember.... My mom was an excellent cook - as a result all of her children were beautiful and healthy! My mom prepared the most delicious platters of food.... Zuccinni, eggplant... broccoli, cabbage, ... Chicken consommĂ© freshly made with 7 vegetables.... and served with egg noodles that she prepared .... and I have continued in her foot steps! Thank God I am still going strong and of course walking every day....I am a mature lady!❤🥊
  • @imhere8380
    2 YEARS AGO.................I felt my brain shutting down and was alarmed I couldn't drive as was confusing the brake and acceleration...........that really shocked me into taking drastic action. I water fast off and on for several months and clean food. CURED....................and overhauled my whole brain. INCREDIABLE.
  • @dg2152
    Fifty one years ago I was ejected from a car traveling at 70mph out the windshield. A traumatic brain injury took several years to to recover from. Praise God for the design of brain regeneration.
  • @LaDeDa0724
    I firmly believe this…while rollerblading one evening, an unknowing brain aneurysm ruptured…as I lay in the hospital bed looking out the window, I was just visualizing blading on Saturday, visualizing in my mind the moves, the music…two months later I was back jogging, nine months later I was back rollerblading! The brain definitely can regenerate!
  • @kellio8087
    After 2 years of research, I believe a high nutrients anti-inflammatory diet along with low impact exercising and a low stress lifestyle is key.
  • Ohhh. After cancer, I fear dementia the most. I just want to live as long as my mind is clear.!! I will do everything possible for that.🤔💯
  • @candrad
    I’m 70 and have had copd over 20 years and been on oxygen and what keeps me alive is excercise which I didn’t start until a few years ago.It makes me breathe better and I’m still learning about diet.This man is the real deal!
  • This is why we need to find a way to get us women in menopause help for sleep. I have perfect sleep hygiene but since menopause falling asleep and staying asleep is almost impossible without turning to meds to help sleep.
  • @sandybayes
    Thank you for inviting Dr Li back! He is one doctor I really feel trust for. He sticks to what's currently known on a topic and presents it in a way to make it easily digestible. I always love your summaries at the end Jonathan. Thank you!
  • @FabioQuirinus
    Nitric Oxide & Infrared therapy seems perfect to complete this topic. The blood vessels are the most important thing in our body! thank you.
  • The late Edgar Cayce who was the Father of Holistic Medicine, and which his research center is still in Virginia Beach, VA - The A.R.E., recommended proper posture for allowing good circulation to the brain. And every morning upon awakening, take three deep breaths or more by inhaling deeply through your nose, and then exhaling through your mouth. This helps release toxins out if your system that accumulated over night. You ca also do this throughout the day, and also be mindful of practicing regular deep breathing throughout the day. The herb Ginko is said to improve blood circulation to the central nervous system, aids in the treatment of dementia and Alzheimers. It also strengthens the blood vascular system and decreasing the possibilities of clots, therefore there is a strong possibility of strokes being prevented. Coconut oil is also shown to help prevent dementia and Alzheimers. Of course, a clean diet, exercise, an adequate sleep are also very important for a healthy brain.
  • @musicloverUK
    This needs teaching in schools. Doctors need teaching about nutrition rather than fobbing us off with pills. Seeing about 80% overweight young adults at a Paramour concert in Brum last year made me realise the younger generation are on a slippery slope to massive health problems. Hell they probably won't even make it to old age if they don't sort themselves out. The way the health service is being shafted they won't even have a free health service to help them. We were sold a lie though about brown bread etc being healthier when in fact, it's just another ultra processed food. Supermarkets have a lot to answer for when up to 80% of the food they sell is processed. Lots of food for thought in this interview thanks. The UK has 40+% obesity rate. We will end up as bad as the US at 66% if we carry carry on as we are.
  • @Shelbymaldita
    Vascular dementia correlates with stroke it is very common in my patients as a RN I've seen it in my patients from a multimillionaire to middle class patients. It doesn't discriminate the social class. We need more funding with research. I noticed that it relates with hard of hearing I experienced with my grandma and my aunt. The surprising fact is it's not genetic.
  • @144Donn
    Dr Li is an absolute National Treasure! All doctors should have.His positivity, kindness and expertise. He understands the "system", not just one aspect of it. He gets the totality of the human body and how they interconnect, from the tip of the toes to the top of the head. Dr Li is the future of medicine! To sum up Dr Li's healthful living: eat a plant based diet & MOVE your body!
  • @carolyn7691
    It sounds like a living body is constantly evolving OR devolving, depending on how it is treated and employed. We need to start taking responsibility for our bodies, rather than abuse them, and then run to the doctor for a fix when they break!
  • @daveoatway6126
    Excellent interview. I am not convinced about a plant based diet, but go out of my way to get plenty of flavonoids and fiber. At 80 years I need more protein and iron. I walk 3-10 miles a day most days, and work out at least 3 days a week. I am still doing successful work as a senior analyst and sail a small boat whenever I can. Major issues are worries about balance, and increasing difficulty with short term memory. Your interviews are very helpful.
  • @itsno1duh
    I had a major surgery in 1990 at 40 yrs of age upped my water to get stamina back but I was following unwise media / MDs and limiting salt for many years by then... in a year or so I developed nonstop excruciating joint pain, another year I couldn't think straight , drive safely or do my job (electrical wiring) just happen on WaterCure site looking for a filter.... Read "your bodies many cries for water" and learned how bad the salt limiting was and adding back correct % turned the dementia around in just a few weeks!! and the staggering pain in a couple months! Seriously salt is LIFE with water in correct amounts.