How fake flavour molecules trick your tongue

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Published 2021-07-01
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Previous video about how taste works:    • What Do Protons Taste Like?  
Video about how sugar twists light:    • Why Sugar Always Twists Light To The ...  
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Artificial sweetener works by binding to your sweetness receptors but they provide no calories. What effect does that have on the sweetness receptors in your gut and can your other taste senses be tricked in the same way: sour, butter, umami (savory) and salt?

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All Comments (21)
  • @SteveMould
    You can discuss this video over on REDDIT if you want: stvmld.com/jrwepagi Bitrex really sticks around in your mouth. I regret filming that bit for real. You can support me on Patreon to get access to the bonus video here: stvmld.com/fbku3aj2 The sponsor is brilliant: The first 200 people to sign up at brilliant.org/stevemould will get 20% off an annual subscription.
  • @luminoustedium
    This is the LockPickingPlant, and what I have for you today is a sweet taste receptor from a mammal. Usually you need sugar to open this, but there is an almost unforgivable amount of sloppiness in this design. I'm going to show you that not only can it be opened with a low-cost protein based attack, but how it's so much easier and more effective than doing it with the proper glucose.
  • @integza
    I was not mentally prepared to see that shot of you pooping in the woods Steve
  • "Gorillas have evolved" Proceeds to show clip of gorilla ferociously eating the boogers from its nose
  • @FraktalPriest
    Steve Mould mentions the words "Benign Masochism", and everything in my life fell instantly into place.
  • @unvergebeneid
    Pooping out seeds right next to a huge established tree is a total dick move. Please be considerate and poop out in the open where the new plants can get plenty of light. That's the deal!
  • @joshuaewalker
    10:44 Steve: "Gorillas have evolved." Cuts to a video of a gorilla picking its nose
  • @sullychow4123
    "Gorillas have evolved their sense of taste". Shows a mummy gorilla eating her bogies while holding her baby. Lovely.
  • @PetrHosek
    This reminded me of a hypothesis I figured out a couple days ago considering the typical "kindergarten puking chain reaction" – it may be beneficial for animals living in groups that they all start vomiting (or at least become more susceptible to it) once one of them shows signs of poisoning just in case more of them ate the poison, maybe a little while after the first puking individual.
  • @spookstory2519
    Hi Steve, I work on taste receptors as part of my PhD! And you're right about the brazzein binding to sweet taste receptors, but it only binds to one half of the complex, T1R3. Curiously the same part that is present in umami complexes, despite not causing an umami taste!
  • @alexsparks651
    You’re exactly what I wish my science teachers could have been like. Engaging, funny, interesting. Your points are often things that would otherwise be difficult to grasp but with your explanations become an interesting topic. Keep up the great work!
  • @famitory
    mint also works like capsaicin, activating the TRPM8 receptor which is intended to trip around 20-26 Celsius to detect cool, but not cold sensation.
  • I didn't think a single video could answer so many of my questions at the same time! Fantasic work, Steve!
  • @davideisner6171
    Your description of hydronium was good up to the point you compared it to the Na+ • 6H2O hydration shell. H3O+ is covalently bonded and also has a shell of H2O molecules that are not covalently bonded to it. It is not the same as just H+ with a hydration shell. It is still written H+ as a shorthand, but was originally written that way because it was thought to exist stably in that form, which is now known to not be the case.
  • So, that time I had a huge piece of cake and decided to have coke zero to compensate...I was actually introducing a Trojan Horse to myself.
  • @msachin4885
    Chillis: create a specialized chemical over millions of years to dissuade mammals from eating them Humans: Now This is some Gourmet Shit right here
  • @nobodynemoq
    I love your sense of humour. It makes your videos much more entertaining, yet still very comprehensive. And... OH MY GOD! I've never thought how brussels sprouts grow! It's hilarious!!! ♥️